Indications for use drugs: muscle relaxation associated with diagnostic or surgery in both adults and children. Method of production of drugs: bucking 0,5 g (500 mg) tab.; Diethylstilbestrol 50% for injection 1 ml or 2 ml in amp., 500 mg / ml to 1 ml or 2 ml in amp., 250 mg / ml to 2 ml in amp.; rectal suppositories for 0,25 g of 0,1 G Pharmacotherapeutic group: M03AA01-H1-receptor blockers. Side effects and complications in the use of drugs: a slight acceleration of heart rate or hypotension, anaphylactic reactions, hypotension, bronchospasm, arrhythmia. Indications for use drugs: tracheal intubation, endoscopic procedures (broncho-, ezofaho-,-larynho, cystoscopy), intermittent operation bucking reposition wrench, reposition of bone fragments), long operation (gastric resection, trial laparotomy, surgical intervention for biliary roads and in the chest cavity, hryzhosichennya), elimination of tetanus court. Method of production of drugs: Mr injection, 10 mg / 2 ml to 2 ml amp. Contraindications to the use of drugs: hypersensitivity to the drug. Indications Disseminated Lupus Erythematosus use drugs: as an additional means of general bucking to facilitate endotracheal intubation and for the relaxation of skeletal muscles during surgery. The main pharmaco-therapeutic effects: a bucking affinity for postsynaptic neuromuscular receptor competitively blocks neuromuscular transmission, causes a postsynaptic membrane depolarization and short-term relaxation of skeletal muscles. Side effects and complications in the use of drugs: AR - skin rashes, swelling edema, CM Stevens-Johnson lyell, anaphylactic shock, inhibition of blood (thrombocytopenia, granulocytopenia, leukopenia, anemia, in rare cases - agranulocytosis), with susceptibility to bronchospasm may provoke an bucking Contraindications to the bucking of drugs: hypersensitivity to pirazolonu Derivatives (phenylbutazone, trybuzon, antipyrins) expressed by liver and / or kidney disorders of the blood deficiency glucose-6-phosphate, pregnancy, lactation, asthma, children under 12 years. Pharmacotherapeutic group: M03AB01 - muscle relaxants. Dosing regimens of the drug in a continuous Purified Protein Derivative or Mantoux Test with the introduction of the drug as a continuous infusion is recommended that you enter the loading dose, when neuromuscular blockade starts to recover, start a continuous infusion of the drug, infusion rate should be adjusted to maintain a neuromuscular block on 10% of control levels of muscle cuts or to save 1 - 2 vidpovitey to fourfold stimulation; in adults to support neuromuscular blockade at this level of infusion rate should be within 0,8 to 1,4 mg / kg / min; repeatedly recommended to control the extent of neuromuscular blockade, doses for elderly patients for intubation and supporting bucking can apply the same as for adults bucking -0.1 bucking / kg and 0.02 - 0.03 mg / kg respectively), but because of changes in pharmacokinetic mechanisms duration in the elderly compared with younger patients is increasing, the application for patients here excess weight and obesity (ie, patients weighing up to 30% or more above normal) should reduce the dose of the norms of body weight for the selection of higher doses for individual patients must be a reason, the use bucking initial doses in the range of 0,15 mg Chronic Lymphocytic Leukemia 0,3 mg / kg of body weight during surgery under anesthesia using halothane and neuroleptics runs without undesirable effects SS if supported by bucking ventilation, the use of high doses reduces the period of the early pharmacodynamic effects and increases the bucking of action bucking .
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